Date of Scholarly Project Submission


Degree Type

Scholarly Project

Degree Name

Doctor of Nursing Practice (DNP)



Faculty Chairperson

Kristi Robinia

Second Committee Member

Theresa Durley

Third Committee Member

Anne Stein


Central line-associated bloodstream infections (CLABSIs) are responsible for increased patient morbidity, mortality, and healthcare costs, despite being a preventable harm (Barnes et al., 2015; Furuya et al., 2016). Evidence-based (EB) research suggests that the use of central line bundles is the most effective way to reduce CLABSIs in hospitals (Barnes et al., 2015; Furuya et al., 2016). Researchers have also found a statistically significant correlation between nurse compliance with bundle components and CLABSI rates (Aloush & Alsaraireh, 2018; Furuya et al., 2016). The purpose of this study was to determine if a nurse-led collaborative that focused on CLABSI reduction using EB prevention strategies, with an emphasis on maintenance bundles, in the form of a Central Line Adult Point Prevalence Tool (CLAPPT), was successful in decreasing CLABSIs at a rural Midwestern hospital. Nurse compliance with the CLAPPT following formal education was also explored. A retrospective analysis of CLABSI rates pre- and post-intervention and nurse compliance was performed. The results of this study showed CLABSI rates and number of catheter days increased, despite an improvement in nurse compliance with the interventions. The global pandemic of 2020 caused the focus of U.S. hospitals to shift from best hospital acquired infection (HAI) control practices to COVID-19 mitigation, which led to an uptick in HAIs nationwide (Centers for Disease Control and Prevention, n.d.-d). Unfortunately, this healthcare facility was no exception.