ST3GAL3 GENE MUTATION WITHIN THE SINGULAR NUCLEOTIDE POLYMORPHISM, RS3952787, POTENTIALLY COULD PREDICT ATTENTION DEFICIT HYPERACTIVE DISORDER, ANXIETY, AND DEPRESSION

Author

Rebecca R. Balinski, Northern Michigan UniversityFollow

Date of Award

4-2025

Degree Type

Thesis

Degree Name

Master of Science

Department

Psychological Science

Program

Psychological Science (MS)

First Advisor/Chairperson

Dr. Amber LaCrosse

Abstract

Certain disorders, like attention deficit hyperactive disorder (ADHD), are challenging to diagnose, particularly via clinical assessment, as the standard diagnostic criteria and testing methods vary among clinicians. ADHD is commonly known as a neurodevelopmental disorder, and as such, certain genetic components may potentially aid in the diagnostic process. Previous and current literature has identified ST3 beta-galactoside alpha-2,3-sialyltransferase 3 (ST3GAL3) as a highly probable genetic component underlying ADHD. This study will primarily investigate the ST3GAL3 gene mutation within a specific single nucleotide polymorphism (SNP) that may be playing a role in the development of ADHD, along with anxiety and depression, as these two disorders are commonly diagnosed alongside ADHD. Loop-mediated isothermal amplification (LAMP) will be the primary assay utilized in this study.

Recommended Citation

Balinski, Rebecca R., "ST3GAL3 GENE MUTATION WITHIN THE SINGULAR NUCLEOTIDE POLYMORPHISM, RS3952787, POTENTIALLY COULD PREDICT ATTENTION DEFICIT HYPERACTIVE DISORDER, ANXIETY, AND DEPRESSION" (2025). All NMU Master's Theses. 877.
https://commons.nmu.edu/theses/877

Access Type

Open Access